{"id":3495,"date":"2023-01-09T16:23:02","date_gmt":"2023-01-09T16:23:02","guid":{"rendered":"https:\/\/www.piamfarmaceutici.com\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/"},"modified":"2023-01-27T11:07:50","modified_gmt":"2023-01-27T11:07:50","slug":"difetti-del-ciclo-dellurea-ucd-2","status":"publish","type":"patologia","link":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/","title":{"rendered":"Urea cycle defects (UCD)"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Urea Cycle Defects are a group of inherited metabolic diseases, characterized by deficiencies in enzymes and transporters involved in the urea cycle, a metabolic pathway dedicated to the transformation of ammonium (produced by the catabolism of amino acids) into urea, which in turn is eliminated from the body via urine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The defects of the urea cycle therefore lead to a reduced elimination of ammonium, which is a highly toxic substance for the central nervous system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some forms of UCD can be treated exclusively through restricting food proteins, in order to reduce the amount of ammonium deriving from their catabolism.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, a low-protein diet may not be able to provide the right amount of essential amino acids that the body needs; for this reason, the patient suffering from urea cycle defects should supplement a low-protein diet with a mix of essential amino acids.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Moreover, in some cases it is necessary to intervene with a specific pharmacological treatment that supports the removal of ammonium.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">PIAM, always attentive to issues related to rare or low-prevalence diseases, offers a range of amino acid mixtures essential for the proper nutritional management of the patient suffering from defects in the urea cycle, providing tailor-made solutions for all ages, from childhood to adulthood.<\/span><\/p>\n","protected":false},"featured_media":3496,"template":"","categoria-patologia":[215],"class_list":["post-3495","patologia","type-patologia","status-publish","has-post-thumbnail","hentry","categoria-patologia-inborn-errors-of-protein-metabolism"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Urea cycle defects (UCD) - PIAM farmaceutici s.p.a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Urea cycle defects (UCD) - PIAM farmaceutici s.p.a\" \/>\n<meta property=\"og:description\" content=\"Urea Cycle Defects are a group of inherited metabolic diseases, characterized by deficiencies in enzymes and transporters involved in the urea cycle, a metabolic pathway dedicated to the transformation of ammonium (produced by the catabolism of amino acids) into urea, which in turn is eliminated from the body via urine. The defects of the urea [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/\" \/>\n<meta property=\"og:site_name\" content=\"PIAM farmaceutici s.p.a\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-27T11:07:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.piamfarmaceutici.com\/wp-content\/uploads\/2023\/01\/difetti_del_ciclo_dell_urea_UCD-6.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1280\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/\",\"url\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/\",\"name\":\"Urea cycle defects (UCD) - PIAM farmaceutici s.p.a\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/difetti_del_ciclo_dell_urea_UCD-6.jpg\",\"datePublished\":\"2023-01-09T16:23:02+00:00\",\"dateModified\":\"2023-01-27T11:07:50+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/difetti_del_ciclo_dell_urea_UCD-6.jpg\",\"contentUrl\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/wp-content\\\/uploads\\\/2023\\\/01\\\/difetti_del_ciclo_dell_urea_UCD-6.jpg\",\"width\":1920,\"height\":1280},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/patologia\\\/difetti-del-ciclo-dellurea-ucd-2\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Urea cycle defects (UCD)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/#website\",\"url\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/\",\"name\":\"PIAM farmaceutici s.p.a\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.piamfarmaceutici.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Urea cycle defects (UCD) - PIAM farmaceutici s.p.a","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/","og_locale":"en_US","og_type":"article","og_title":"Urea cycle defects (UCD) - PIAM farmaceutici s.p.a","og_description":"Urea Cycle Defects are a group of inherited metabolic diseases, characterized by deficiencies in enzymes and transporters involved in the urea cycle, a metabolic pathway dedicated to the transformation of ammonium (produced by the catabolism of amino acids) into urea, which in turn is eliminated from the body via urine. The defects of the urea [&hellip;]","og_url":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/","og_site_name":"PIAM farmaceutici s.p.a","article_modified_time":"2023-01-27T11:07:50+00:00","og_image":[{"width":1920,"height":1280,"url":"https:\/\/www.piamfarmaceutici.com\/wp-content\/uploads\/2023\/01\/difetti_del_ciclo_dell_urea_UCD-6.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/","url":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/","name":"Urea cycle defects (UCD) - PIAM farmaceutici s.p.a","isPartOf":{"@id":"https:\/\/www.piamfarmaceutici.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/#primaryimage"},"image":{"@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/#primaryimage"},"thumbnailUrl":"https:\/\/www.piamfarmaceutici.com\/wp-content\/uploads\/2023\/01\/difetti_del_ciclo_dell_urea_UCD-6.jpg","datePublished":"2023-01-09T16:23:02+00:00","dateModified":"2023-01-27T11:07:50+00:00","breadcrumb":{"@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/#primaryimage","url":"https:\/\/www.piamfarmaceutici.com\/wp-content\/uploads\/2023\/01\/difetti_del_ciclo_dell_urea_UCD-6.jpg","contentUrl":"https:\/\/www.piamfarmaceutici.com\/wp-content\/uploads\/2023\/01\/difetti_del_ciclo_dell_urea_UCD-6.jpg","width":1920,"height":1280},{"@type":"BreadcrumbList","@id":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/difetti-del-ciclo-dellurea-ucd-2\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.piamfarmaceutici.com\/en\/"},{"@type":"ListItem","position":2,"name":"Urea cycle defects (UCD)"}]},{"@type":"WebSite","@id":"https:\/\/www.piamfarmaceutici.com\/#website","url":"https:\/\/www.piamfarmaceutici.com\/","name":"PIAM farmaceutici s.p.a","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.piamfarmaceutici.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/patologia\/3495","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/patologia"}],"about":[{"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/types\/patologia"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/media\/3496"}],"wp:attachment":[{"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/media?parent=3495"}],"wp:term":[{"taxonomy":"categoria-patologia","embeddable":true,"href":"https:\/\/www.piamfarmaceutici.com\/en\/wp-json\/wp\/v2\/categoria-patologia?post=3495"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}