{"id":3474,"date":"2023-01-09T16:47:37","date_gmt":"2023-01-09T16:47:37","guid":{"rendered":"https:\/\/www.piamfarmaceutici.com\/patologia\/ulcere-flebostatiche\/"},"modified":"2023-01-09T16:47:37","modified_gmt":"2023-01-09T16:47:37","slug":"ulcere-flebostatiche","status":"publish","type":"patologia","link":"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/ulcere-flebostatiche\/","title":{"rendered":"Phlebostatic ulcers"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">The extreme evolution of chronic venous insufficiency is the <strong>phlebostatic ulcer<\/strong>, which is the most serious expression of venous stasis skin pathology.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In its most typical form it is localized to the malleolus and the skin already subject to other alterations due to venous insufficiency.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ulcers almost always tend towards chronicization and remain in a phlogistic \/ infectious stage very often due to a bacterial colonization that contributes to their lack of scarring; in this regard, recent studies demonstrate that the chronicity of an ulcer is sometimes related to the contamination of <\/span><b>bacteria producing biofilms<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Precisely because of the correlation between chronic ulcers and contamination by biofilm-producing bacteria, research has turned towards anti-biofilm agents and, among these, towards lactoferrin in particular which, thanks to its iron-chelating properties, is able to deconstruct the biofilm matrix composed of polysaccharides held together by iron atoms.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">PIAM, aware of the seriousness of this debilitating pathology, today makes available innovative solutions that can meet the needs of the patient.<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":3475,"template":"","categoria-patologia":[222],"class_list":["post-3474","patologia","type-patologia","status-publish","has-post-thumbnail","hentry","categoria-patologia-aesthetic-and-vascular-medicine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Phlebostatic ulcers - PIAM farmaceutici s.p.a<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.piamfarmaceutici.com\/en\/patologia\/ulcere-flebostatiche\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Phlebostatic ulcers - PIAM farmaceutici s.p.a\" \/>\n<meta property=\"og:description\" content=\"The extreme evolution of chronic venous insufficiency is the phlebostatic ulcer, which is the most serious expression of venous stasis skin pathology. 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